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Post-doctoral position in molecular biology - Modelling early embryonic development in vitro using stem cells

Research / Academic
Maastricht

The MERLN Institute for Technology-Inspired Regenerative Medicine is seeking a post-doctoral scientist to join our team in bringing stem cell-based embryo models to the next level. This position is part of the ‘Synthetic Embryo’ project in which these models are harnessed to assist in revealing the hidden processes of newly forming life, to battle fertility and reproduction problems, and explore the embryonic origin of diseases.

We are looking for a creative thinker who is prepared to take on highly challenging aims. The project will be highly collaborative and interdisciplinary and will suit an ambitious candidate who likes a fast-paced environment.

We encourage applications from individuals with a strong background in cell/development and molecular biology and who are passionate to investigate processes involved in stem cell identity, differentiation and early lineage specification (epiblast/trophoblast).

Responsibilities

  • Employing CRISPR-mediated gene editing and single-cell sequencing (in collaboration with a bio-informatician) to answer questions related to early embryonic development.
  •  Design and rigorous execution of experimental work, data analysis and dissemination of results
  • Using tailored cutting-edge microfabricated tools as culture platform for stem cell-based embryo models

Requirements:

  • PhD or equivalent with experience in Molecular Cloning and/or Gene editing systems (e.g. CRISPR/Cas9
  •  Strong background in Cell or Developmental Biology, preferably with experience in Pluripotent Stem Cell culture
  • Creative thinker that can independently deepen a research question
  • Excellent communicator (oral and written English) and team worker
  • Solid experience in experimental design
  • Article 9 of the Wet op de Dierproeven (WOD, Experiments on Animals Act) or similar is not required but is a plus
  • Knowledge of Dutch is not required.

Salary Benefits:

  • Fixed-term contract of 1 + 2 years (evaluation after first year), full-time position. The salary will be set according post-doc salary scale 10 of the Collective Labor Agreement of the Dutch Universities (CAO-NU); between € 2.709, - gross per month and € 4.274, - gross per month. On top of this, there is an 8% holiday and an 8.3% year-end allowance.
  • Candidates who would need to relocate may be eligible for compensation. Employees relocating from abroad may be eligible for the Dutch `30% ruling', a tax advantage which results in a significantly higher net salary. The terms of employment of Maastricht University are set out in the Collective Labour Agreement of Dutch Universities (CAO-NU) and local UM provisions also apply.
  •  A fully resourced and funded research environment, office space fostering interaction between multi-disciplinary researchers and engineers.
Work Hours:

38 hours per week

Address:

Universiteitssingel 40