PhD Candidate for Molecular Neurobiology
Updated: 29 Feb 2020
A PhD Candidate to work on a genetic screen to identify genes that are required for axonal maintenance. After screening ~20% of the Drosophila genome, we have identified ~45 mutant lines that display axonal degeneration, showing that the screening approach works.
You will work on the characterisation of mutants already identified, and the generation of additional mutants, followed by whole genome sequencing and bio-informatic analysis to identify causative mutations, and putative disease-causing mutations in the human orthologous genes. You will further have the opportunity to contribute to other ongoing projects in our lab and be able to use a broad spectrum of methods and techniques including Drosophila genetics and behavioural analysis, fluorescence and confocal microscopy (and if applicable also super-resolution and electron microscopy), Illumina next-generation sequencing, immunohistochemistry, molecular biology and biochemistry. You will be expected to supervise Master's students. Beyond that, your exposure to teaching will be minimal.
- You are a highly motivated, enthusiastic, critical, creative and team-oriented individual with a particular interest in neurobiology.
- You hold a Master's degree (or are about to obtain one) in biology, biomedical sciences, biochemistry, genetics or a related discipline, and are interested in a scientific career.
- Previous experience with Drosophila genetics would be a plus but is not required.
- We are a dynamic international lab, so a good command of English is essential.
- You are capable of working in a team as well as independently.
- Employment: 40 hours per week.
- The gross starting salary amounts to €2,325 per month, and will increase to €2,972 in the fourth year (p scale).
- In addition to the salary: an 8% holiday allowance and an 8.3% end-of-year bonus.
- Duration of the contract: you will be appointed for an initial period of 18 months, after which your performance will be evaluated. If the evaluation is positive, the contract will be extended by 2.5 years.
- The intended start date is from April 1st 2020 onwards.
- Membership of the Donders Graduate School, including offers such as peer coaching and a mentoring programme.
- Excellent personal development opportunities in both scientific and academic career skills.
- You will be able to make use of our Dual Career Service: our Dual Career Officer will assist with family-related support, such as child care, and help your partner prepare for the local labour market and with finding an occupation.
- Are you interested in our excellent employment conditions?
40 hours per week